Review Opening Up to Lung Recruitment. Pulmonary Contusion and Derecruitment – The Role of Inflammation Jack J. Haitsma, Karsten Bartels, Peter J. Papadakos Purpose of review: It was recently reported that a lung protective ventilation strategy resulted in no fatalities in 17…
Review Clevidipine: A Unique Agent for the Critical Care Practitioner Gabriela Rodríguez, Joseph Varon Clevidipine is a new third generation intravenous dihydropyridine calcium channel blocker. It is a specific arterial vasodilator developed for…
Review IABP deployment in critical care Hafil B. Abdulgani, Dicky A. Wartono The Intra Aortic Balloon Pump (IABP) is an established support in addition to pharmacologic treatment of the failing heart…
Review Lactate is the ultimate oxidative energy substrate in brain and elsewhere Avital Schurr Now-a-days, the focus on lactate is due to its being an oxidative substrate for energy metabolism in brain (and…
Review Spontaneous breathing during mechanical ventilation in ARDS Ross Freebairn, Keith Hickling The objective of mechanical ventilation used in the management of Acute Respiratory Distress Syndrome (ARDS) is to ensure adequate…
Review Is there any need for higher PEEP levels in ARDS patients? Jack J Haitsma, R.A. Lachmann, Burkhard Lachmann Lung protective ventilation has been shown to reduce mortality in ARDS patients. Current guidelines are focussed on lowering tidal…
Review Fluid resuscitation: the good, the bad and the ugly AB Johan Groeneveld, Polderman KH Fluid resuscitation is one of the most common therapeutic steps in the critically ill. In this brief overview, the…
Review Pyrexia in the critically ill N R Webster Temperature change is a conserved physiological response to infection. In animal studies cytokine responses associated with body temperature changes…
Review Hypoxic tissue damage and the protective effects of therapeutic hypothermia Hector Salazar Reyes, Joseph Varon Several molecules, chemicals and cells are involved in tissue damage during any hypoxic event, such as a cardiac arrest,…
Review Life-threatening hyponatremia in marathon runners: The Varon-Ayus syndrome revisited Pilar Acosta, Joseph Varon Life-threatening hyponatremia can occur when sodium concentration falls to 125 mmol/L or less. Symptoms usually do not depend on…