Original The transpulmonary pressure as an indicator of lung stress in the disorder of chest wall mechanics in pediatric acute lung injury: Study in pig model Ririe Fachrina Malisie, Gunanti Soeyono, Agus Firmansyah Abstract Objectives: To determine the role of the end-inspiratory transpulmonary pressure as an indicator of the lung stress in…
Original Interleukin-10 polymorphisms and clinical risk factors in children with severe sepsis and septic shock Rujipat Samransamruajkit, Krittiya Nakornchai, Khemmachart Pongsanon, Jitladda Deerojanawong, Suchada Sritippayawan, Nuanchan Prapphal Abstract Background: Interleukin-10 (IL-10) is an important anti-inflammatory cytokine that play a key role in sepsis. It is a…
Original Modeling comparative effectiveness studies: An example using a phase IV intravenous nicardipine versus labetalol in patients with uncontrolled hypertension trial W. Frank Peacock, Earvin Liang, Long Kwei, Robert J. Korsan, Michelle L. Green, Bill Poland, Meina T. Tang, Joseph Varon Abstract Background: Hypertension is a common acute presentation that requires effective medication for control. Few comparative effectiveness trials exist…
Original The effect of the antioxidant drug “U-74389G” on sodium levels during ischemia reperfusion injury in rats C. Τsompos, C. Panoulis, K. Τοutouzas, G. Ζografos, A. Papalois Abstract Background: The aim of this experimental study was to examine the effect of the antioxidant drug “U-74389G” testing,…
Original Deep sedation contributes to high release of hypoxic pulmonary vasoconstriction in mechanically ventilated acute respiratory distress syndrome patients Jun-ichi Hirata, Munehiko Ohya, Seishiro Marukawa, Keiji Kumon Abstract Background: We report the cases of 2 patients with severe pneumonia who exhibited increased changes in hypoxic pulmonary…
Original Perioperative upper airway edema: Risk factors and management Jonas P. DeMuro, Michael N. Mongelli, Adel F. Hanna Abstract Objectives: To study the risk factors and treatment of the postoperative patient who develops upper airway edema. Design:…
Original Study of tracheostomized patients in Intensive Care Unit Chang Li Li, Lau Chun Wing, Lam Sin Man, Shum Hoi Ping, Chan King Chung Kenny, Yan Wing Wa Abstract Objectives: To describe the short-term and long-term outcomes of tracheostomized Intensive Care Unit (ICU) patients and to identify…
Original Therapeutic hypothermia after cardiac arrest: A survey of practice in the intensive care units (ICU) in Hong Kong Alwin Yeung Wai Tak, Yan Wing Wa, Anne Leung Kit Hung, Chow Fu Loi, Polly Tsai, Chan Hok Sum, Luk Ming Chi Abstract Background: Previous studies showed that therapeutic hypothermia after out-of-hospital ventricular fibrillation arrest significantly improved neurological outcome and survival….
Original The effects of probiotics during refeeding period on jejunum mucosal morphology after short-term starvation in Wistar rats Alifi Maulidyan, Dikki Drajat Kusmayadi, Bethy S. Hernowo, Tri Wahyu Murni Abstract Aim: A period of enteral feeding absence is known to cause intestinal atrophy, damaging mucosal barrier and decrease…
Original Prediction model for length of intubation with assisted mechanical ventilation in pediatric heart surgery Eva M. Marwali, Novik Budiwardhana, Sudigdo Sastroasmoro, Antonius Pudjiadi, Nikolaus A. Haas Abstract Objective: To establish a prediction model for intubation time in children undergoing heart surgery. Design: Retrospective chart review….