Original Interleukin-10 polymorphisms and clinical risk factors in children with severe sepsis and septic shock Rujipat Samransamruajkit, Krittiya Nakornchai, Khemmachart Pongsanon, Jitladda Deerojanawong, Suchada Sritippayawan, Nuanchan Prapphal Abstract Background: Interleukin-10 (IL-10) is an important anti-inflammatory cytokine that play a key role in sepsis. It is a…
Original Modeling comparative effectiveness studies: An example using a phase IV intravenous nicardipine versus labetalol in patients with uncontrolled hypertension trial W. Frank Peacock, Earvin Liang, Long Kwei, Robert J. Korsan, Michelle L. Green, Bill Poland, Meina T. Tang, Joseph Varon Abstract Background: Hypertension is a common acute presentation that requires effective medication for control. Few comparative effectiveness trials exist…
Original The effect of the antioxidant drug “U-74389G” on sodium levels during ischemia reperfusion injury in rats C. Τsompos, C. Panoulis, K. Τοutouzas, G. Ζografos, A. Papalois Abstract Background: The aim of this experimental study was to examine the effect of the antioxidant drug “U-74389G” testing,…
Images in clinical medicine Successful treatment of a massive pulmonary embolism using alteplase in a patient taking antipsychotic drugs Jun-ichi Hirata, Munehiko Ohya, Seishirou Marukawa, Keiji Kumon An increased risk of pulmonary embolism (PE) has been reported in female patients taking antipsychotic drugs. Furthermore, patients who…