Abstract
Objective: This study aims to determine the pattern of germs and antibiotic sensitivity in septic patients treated with culture-based antibiotics.
Design: This study was designed for observational-descriptive retrospective.
Setting: The medical record of Dr. Wahidin Sudirohusodo Hospital from January 2018 to January 2022.
Patient and participants: All patients who were diagnosed with sepsis and had data on bacterial culture and treatment with antibiotics.
Interventions: We took blood culture data of patients diagnosed with sepsis from medical records.
Measurement and results: The pattern of bacteria found was Gram-negative bacteria, with the most abundant bacteria being Burkholderia cepacia (37.93%), followed by Acinetobacter baumannii (24.14%), and Klebsiella pneumoniae (10.34%). The highest antibiotic sensitivity was obtained for tigecycline with 88.89% followed by levofloxacin with 78.57%. The lowest antibiotic sensitivity was found in ampicillin, ampicillin/sulbactam, and cefoperazone/sulbactam as much as 0% or all of these antibiotics showed results that were resistant to culture results.
Conclusions: Gram-negative bacteria are the main cause of septic patients with varying antibiotic sensitivity depending on the type of antibiotic used.
Faisal Muchtar, Haizah Nurdin, Hisbullah, Ari Santri, Muhammad Rum, Fradita Yudiastri Yunus Guzasiah
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- Bacterial patterns and antibiotic sensitivity in sepsis patients treated with culture-based antibiotics in intensive care
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