Abstract
Introduction: According to the World Health Organization (WHO), sepsis is currently the leading cause of mortality and critical illness worldwide, with a reported mortality rate of 28.6% among the population and, therefore, belongs to one of the leading causes of maternal death, with a percentage record of 11%.
Objective: To determine the prevalence and clinical characteristics of maternal sepsis in the Intensive Care Unit (ICU) of a tertiary care center in Mexico from January 1, 2019 to February 28, 2022.
Materials and methods: Retrospective, cross-sectional, descriptive study. All the records of patients admitted to the ICU of the Women’s Hospital of Sinaloa during the aforementioned period were included, and those with a diagnosis of maternal sepsis were selected.
Results: The prevalence of maternal sepsis was 11.2%. The predominant age was 25 to 32 years (34.37%). Sixteen primiparous (50%), 8 secondiparous (25%), 8 multiparous (25%); 15 in puerperium (46.8%), 12 pregnant (2 twins, 1 deceased) (37.5%), and 5 failed deliveries (15.6%). Infectious foci: kidney and urinary tract in 15 patients (42%), pelvis (uterus and adnexa) in 13 patients (36%), abdomen in 5 patients (14%), and lung in 3 cases (14%). Escherichia coli was the most frequent pathogen (n=5), followed by Klebsiella and Enterococcus (each 1 patient), respectively. Comorbidities: 5 with severe preeclampsia (15.6%), 1 gestational diabetes, 1 nephrotic syndrome (3.1%); 17 normal weight (53%), 12 overweight (38%), and 3 obese (9%). Mortality: 3 cases (9.3%).
Conclusions: The prevalence of maternal sepsis was 11.2%. Characteristics: age between 25-32 years; primiparous women, puerperium, kidney/urinary tract as the most frequent source of infection, and Escherichia coli was the most common pathogen.
Ania Cecilia Osuna Sanchez, Francisco Castro Apodaca, Marco Aurelio Espero Cardenas, Adrian Canizalez-Roman, Jorge Angulo-Rocha, Mario Francisco Barajas-Olivas, Joseph Varón, Joel Murillo-Llanes
