Abstract
Background: Weaning from mechanical ventilation is essential for critically ill patients and obtaining mechanical ventilation. Several parameters were used to assess the patient’s ability to predict the success of weaning.
Objective: The purpose of this study was to determine the accuracy of diaphragm thickening fraction, C-reactive protein, cumulative fluid balance, and rapid shallow breathing index in predicting the ease of weaning mechanical ventilation in critical patients in the intensive care unit (ICU).
Method: This was a prospective cohort study in which the subjects were adult patients who were treated using mechanical ventilation. Diaphragm thickening fraction, C-reactive protein, cumulative fluid balance, and rapid shallow breathing index were examined during the first 24 hours in the ICU and during mechanical ventilation in pressure support (PS)<8 or T-piece mode until a maximum of the seventh day of the treatment in the ICU or on the seventh day if have not been successfully weaned.
Result: We found that there was no statistical significance between the diaphragm thickening fraction and the ease of weaning from mechanical ventilation (p=0.071). The effect of C-reactive protein on the ease of weaning on mechanical ventilation was not statistically significant (p=0.724). The cumulative balance and rapid shallow breathing index values were also not statistically significant to predict the ease of mechanical ventilation weaning (p=0.510 and p=0.116)
Conclusion: Diaphragm thickening fraction, C-reactive protein, cumulative fluid balance, and rapid shallow breathing index statistically cannot predict the ease of weaning mechanical ventilation in critical patients in the ICU.
Rudy Nugroho, Indro Mulyono, Yohanes WH George
