Crtical Care and Shock Journal

Use of levocarnitine as an alternative treatment for non-anticoagulant rodenticide poisoning

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Abstract

The objective of this text is to inform and motivate further investigation about the use of levocarnitine as an alternative antidote in patients poisoned by non-anticoagulant rodenticides in a kind of retrospective study through the report of 3 serial cases presented in the Intensive Care Unit (ICU) of the General Hospital Zacatecas ‘Luz González Cosío’, in Zacatecas, Mexico. Two of them were intoxicated with zinc phosphide and one with sodium fluoracetate, all with similar signs and symptoms. In addition to having received vital support measures in the ICU, levocarnitine was administered intravenously, with remission of symptoms in the short term and hospital discharge without apparent sequelae. Therefore, it is appropriate to consider future research on the use of levocarnitine in this kind of patients, in addition to vital support measures.

Omar Alberto Venegas Gurrola, Mónica Rodríguez Borroel, Omar Uriel Sánchez Alba, César Fabián Díaz García

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