Crtical Care and Shock Journal

Successful use of extracorporeal membrane oxygenation in a patient with transfusion-related acute lung injury

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Objective: Transfusion-related acute lung injury (TRALI) is a relatively uncommon complication in patients who undergo plasma-containing blood product transfusion. Despite the cross matching process, TRALI remains the most common cause of mortality associated with transfusion. We describe a case of TRALI in a 24-year-old trauma patient who was successfully cared for on extracorporeal membrane oxygenation (ECMO).

Design: Chart review.

Setting: Academic medical center with Level 1 Trauma.

Patients and participants: Single case from a busy urban trauma center.

Interventions: Extracorporeal membrane oxygenation.

Conclusion: ECMO has only rarely been successfully used in patients with TRALI; to our knowledge, ours is the first successful report of its use in a trauma patient. Its use in maintaining gas exchange in trauma patients with TRALI should be further investigated.

Jarrod Mosier, Terence O’Keeffe, Holly Graham, Peter M. Rhee


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June 2024, Volume 27 Number 3
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