Background: Sepsis is a syndrome of physiological, pathological, and biochemical abnormalities caused by infection. This study aimed to analyze the prevalence and risk factors for sepsis at Pembinaan Kesejahteraan Umat (PKU) Muhammadiyah Gamping Hospital, Yogyakarta.
Methods: The research design was an analytic observational study using a cross-sectional design. The sample in this study were patients diagnosed with sepsis at the hospital from January 2019 to December 2022 and met the inclusion and exclusion criteria. The inclusion criteria were inpatients at the hospital from January 2019 to December 31, 2022, and patients diagnosed with sepsis according to the hospital protocol. Exclusion criteria were patients diagnosed with bacteremia but incomplete data. Sampling was conducted by consecutive sampling. Retrieval of data from patient data stored in medical records. The ethical permit was from PKU Muhammadiyah Gamping Hospital with the number 051/KEP-PKU/III/2023.
Results: The effect of length of stay, diabetes mellitus (DM), and age on the incidence of sepsis was 22.5%. Length of stay had an effect on the incidence of sepsis with a p-value of 0.001. The odds ratio (OR) value was 3.177 (95% CI 2.033-4.965) meaning that a stay of more than 3 days had a risk of suffering from sepsis 3 times greater than a stay of less than 3 days. DM had an effect on the incidence of sepsis with a p-value of 0.009, OR 4.988 (95% CI 1.499-16.601) meaning that patients with DM were at risk of suffering from sepsis 5 times greater than patients who did not suffer from DM. Age had an effect on the incidence of sepsis with a p-value of 0.001, OR 4.162 (95% CI 2.660-6.512) meaning that over 60 years of age, the risk of suffering from sepsis was 4 times greater than patients under the age of 60 years.
Conclusion: The prevalence of sepsis for 4 years was 200 cases. The risk factors that were found to be significant were length of stay, DM, and age. The incidence of sepsis is very important to reduce by adhering to the management of this disease so that it is expected that the cost, length of stay, and high mortality from sepsis can be reduced.