Critical Care and Shock

Calciphylaxis: A case report and literature review

Abstract

Necrotising fasciitis is an extremely life-threatening condition, which mainly develop from the necrosis of the subcutaneous fascia and adjacent tissue. It can be caused recurrently from moderate to severe systemic toxicity and be fatal due to lack of medical or surgical treatment. Any absence of particular clinical features can easily result in the under diagnosis such as cellulites or abscess.

The infection can be caused by one or more micro-organisms, both aerobic and anaerobic. Calciphylaxis or calcific uremic arteriolopathy (CUA) is a rare limb threatening condition commonly seen in renal disease patients. It is commonly caused by the accumulation of calcium deposits in the subcutaneous tissue and in the small arteries. Hence, we report a case of 50-year-old female with necrotising fasciitis who was diagnosed with a very rare condition of calciphylaxis.

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