Critical Care and Shock

Unusual presentation of clozapine-induced abdominal compartment syndrome

Clozapine-induced gastrointestinal hypomotility is common side effect of this drug. It can lead to various degrees of colon obstruction. In rare cases, it can be life-threatening since severe colon obstruction can lead to colon perforation, colon necrosis and ischemia and septic shock. In all these cases, there had been some complaints of constipation or abdominal symptoms prior fatal event. Here, we are reporting a case that had rapidly progressed to cardiac arrest in which the initial symptom was dyspnea instead of abdominal complaint.

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