Critical Care and Shock

Antimicrobial resistance patterns of Staphylococcus aureus in the intensive care unit at a tertiary hospital

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Purpose: The objective of the present study is to determine the pattern of antimicrobial resistance of Staphylococcus aureus (S. aureus) in the Intensive Care Unit at a tertiary hospital in Mexico.

Methods: 1,511 cultures in general surgery, internal medicine, neurosurgery and the ICU were analyzed, the sample pool was limited to ICU patients and out of those, only samples positive for S. aureus were included, meticillin resistance was confirmed.

Results: Of a total of 1,511 samples, 206 (13.63%) were culture positive for S. aureus. In the ICU, antimicrobial resistance to beta-lactams (penicillin, ampicillin, cephalothin, cefotaxime, cefazolin, amoxicillin/Ac. clavulanate and imipenem) averaged 73.52%; for clindamycin was 65.12%; ciprofloxacin 59.09%, erythromycin 65.31% and for vancomycin was 6.52%.

Conclusions: The present study showed a high incidence of MRSA in an Intensive Care Unit at a tertiary hospital.